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    發布時間:2022-07-19 14:37 原文鏈接: 受體酪氨酸激酶信號通路相關FGF6

    該基因編碼的蛋白是成纖維細胞生長因子(fgf)家族的一員。fgf家族成員具有廣泛的有絲分裂和細胞存活活性,參與胚胎發育、細胞生長、形態發生、組織修復、腫瘤生長和侵襲等多種生物學過程。該基因在轉染哺乳動物細胞時表現出致癌轉化活性。該基因的小鼠同系物主要在肌源性譜系中表現出一種限制性表達譜,提示其在肌肉再生或分化中的作用。[由RefSeq提供,2008年7月]
    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation. [provided by RefSeq, Jul 2008]

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