該細胞周期調控基因編碼一種蛋白質,介導富含亮氨酸的核輸出信號(NES)依賴性蛋白質轉運。該蛋白特異性地抑制rev和u-snrnas的核輸出。它通過控制細胞周期蛋白B、MPAK和MAPKAP激酶2的定位,參與控制一些細胞過程。這種蛋白質還調節NFAT和AP-1。[由RefSeq提供,2015年1月]
This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015]