這個基因編碼絲氨酸/蘇氨酸蛋白激酶家族的一個成員。編碼蛋白是一種細胞因子激活蛋白復合物的組成部分,它是必需轉錄因子nf-kappa-b復合物的抑制劑,磷酸化位點通過增溶途徑觸發抑制劑的降解,從而激活轉錄因子。[由RefSeq提供,2008年7月]
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]