這個基因編碼一個絲氨酸/蘇氨酸p21激活激酶家族成員，稱為pak蛋白。這些蛋白是連接rhogtpase與細胞骨架重組和核信號傳導的關鍵效應器，它們是小gtp結合蛋白cdc42和rac的靶點。這個特殊的家族成員調節細胞的運動和形態。另外，已經發現該基因編碼不同亞型的剪接轉錄變體。
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]